Impact of Mail-based Intervention on Adherence to Direct Oral Anticoagulants Among Medicare and Medicaid Beneficiaries

Medication nonadherence affects nearly half of patients receiving chronic therapies and continues to be a significant driver of poor outcomes and rising health care costs. Although direct oral anticoagulants (DOACs) offer established clinical benefits, less frequent monitoring can make it harder for some patients to stay on therapy over time. Mail-based interventions may provide insight into strategies that improve adherence among Medicare and Medicaid beneficiaries and support better long-term outcomes.